A MAPT mutation in a regulatory element upstream of exon 10 causes frontotemporal dementia
We report here the genetic analysis of a newly ascertained kindred in which frontotemporal dementia occurs in an apparent autosomal dominant fashion, and in which a novel MAPT gene mutation co-segregates with disease. Sequencing the MAPT gene in affected individuals revealed a change in intron 9. Th...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2006-05-01
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| Serija: | Neurobiology of Disease |
| Teme: | |
| Online pristup: | http://www.sciencedirect.com/science/article/pii/S0969996105003360 |
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