Successful Dendrimer and Liposome-Based Strategies to Solubilize an Antiproliferative Pyrazole Otherwise Not Clinically Applicable

Water-soluble formulations of the pyrazole derivative 3-(4-chlorophenyl)-5-(4-nitrophenylamino)-1<i>H</i>-pyrazole-4-carbonitrile (CR232), which were proven to have in vitro antiproliferative effects on different cancer cell lines, were prepared by two diverse nanotechnological approaches. Important...

Descripció completa

Dades bibliogràfiques

Autors principals:	Silvana Alfei, Andrea Spallarossa, Matteo Lusardi, Guendalina Zuccari
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-01-01
Col·lecció:	Nanomaterials
Matèries:	fifth-generation polyester-based lysine-modified dendrimer physical encapsulation 3-(4-chloro-phenyl)-5-(4-nitro-phenylamino)-1<i>H</i>-pyrazole-4-carbonitrile (CR232) water-soluble CR232-loaded dendrimer NPs water-soluble CR232-loaded liposomes spherical morphology
Accés en línia:	https://www.mdpi.com/2079-4991/12/2/233
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!