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Cerebrospinal fluid Circulating Tumor DNA (ctDNA) as a biomarker for CNS metastases in Non-Small Cell Lung Cancer (NSCLC): a systematic review and meta-analysis comparing CSF ctDNA and traditional methods

Abstract Background Brain metastasis is a common and serious complication in patients with non-small cell lung cancer (NSCLC), often associated with poor prognosis. While traditional diagnostic approaches such as magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) cytology are commonly us...

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Principais autores: Oluwatobi O. Olayode, Blessing T. Ogunoye, Emmanuel Olusola Oladeji, Oluwafemi E. Olayinka, Tolulope J. Oladosu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-07-01
coleção:BMC Cancer
Assuntos:
CSF ctDNA
Brain metastases
NSCLC
Liquid biopsy
Diagnostic accuracy
Biomarker
Acesso em linha:https://doi.org/10.1186/s12885-025-14583-1
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