Dynamic changes in tumor profiling reveal intra- and inter-tumoral heterogeneity focused on an uncharacterized HER2 mutation: a case report of a young breast cancer patient

Despite multiple recent advances in systemic therapy for metastatic breast cancer, cases which display suboptimal response to guideline-driven treatment are frequently seen in the clinic. Effective options for such patients are limited, particularly in later line of therapy, and selection of optimal...

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Hlavní autoři:	Dörthe Schaffrin-Nabe, Anke Josten-Nabe, Andrea Tannapfel, Waldemar Uhl, Marietta Garmer, Razelle Kurzrock, Timothy Crook, Sewanti Limaye, Stefan Schuster, Darshana Patil, Merle Schaffrin, Kefah Mokbel, Rudolf Voigtmann
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-05-01
Edice:	Frontiers in Oncology
Témata:	personalized therapy precision oncology metastatic breast cancer extensive tumor profiling treatment strategies
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1395618/full
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