Heterogeneous Tau Oligomers as Molecular Targets for Alzheimer’s Disease and Related Tauopathies

Tauopathies, including Alzheimer’s disease (AD), are a group of neurodegenerative disorders characterized by pathological aggregation of microtubule binding protein tau. The presence of tau neurofibrillary tangles, which are insoluble β-sheet fibrils, in the brain has been the histopathological hall...

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Hlavní autor:	Chih Hung Lo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-11-01
Edice:	Biophysica
Témata:	tau oligomers and aggregates cellular and pathological heterogeneity neurotoxicity conformational ensembles protein-protein interaction molecular diversity
On-line přístup:	https://www.mdpi.com/2673-4125/2/4/39
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