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The landscape of coding RNA editing events in pediatric cancer

Abstract Background RNA editing leads to post-transcriptional variation in protein sequences and has important biological implications. We sought to elucidate the landscape of RNA editing events across pediatric cancers. Methods Using RNA-Seq data mapped by a pipeline designed to minimize mapping am...

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Autori principali: Ji Wen, Michael Rusch, Samuel W. Brady, Ying Shao, Michael N. Edmonson, Timothy I. Shaw, Brent B. Powers, Liqing Tian, John Easton, Charles G. Mullighan, Tanja Gruber, David Ellison, Jinghui Zhang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2021-11-01
Serie:BMC Cancer
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Accesso online:https://doi.org/10.1186/s12885-021-08956-5
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