Theoretical and experimental analysis links isoform‐ specific ERK signalling to cell fate decisions

Abstract Cell fate decisions are regulated by the coordinated activation of signalling pathways such as the extracellular signal‐regulated kinase (ERK) cascade, but contributions of individual kinase isoforms are mostly unknown. By combining quantitative data from erythropoietin‐induced pathway acti...

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Detalhes bibliográficos

Principais autores:	Marcel Schilling, Thomas Maiwald, Stefan Hengl, Dominic Winter, Clemens Kreutz, Walter Kolch, Wolf D Lehmann, Jens Timmer, Ursula Klingmüller
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer Nature 2009-12-01
coleção:	Molecular Systems Biology
Assuntos:	cytokine receptor ERK information processing proliferation sensitivity analysis
Acesso em linha:	https://doi.org/10.1038/msb.2009.91
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