Lactobacillus-derived extracellular vesicles counteract Aβ42-induced abnormal transcriptional changes through the upregulation of MeCP2 and Sirt1 and improve Aβ pathology in Tg-APP/PS1 mice

Abstract Mounting evidence suggests that probiotics are beneficial for treating Alzheimer’s disease (AD). However, the mechanisms by which specific probiotics modify AD pathophysiology are not clearly understood. In this study, we investigated whether Lactobacillus paracasei-derived extracellular ve...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Hyejin Kwon, Eun-Hwa Lee, So-Young Park, Jin-Young Park, Jin-Hwan Hong, Eun-Kyung Kim, Tae-Seop Shin, Yoon-Keun Kim, Pyung-Lim Han
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Publishing Group 2023-09-01
Цуврал:	Experimental and Molecular Medicine
Онлайн хандалт:	https://doi.org/10.1038/s12276-023-01084-z
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!