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Characterisation of European Field Goat Prion Isolates in Ovine PrP Overexpressing Transgenic Mice (Tgshp IX) Reveals Distinct Prion Strains

After the detection of bovine spongiform encephalopathy (BSE), and a zoonotic transmissible spongiform encephalopathy (TSE) caused by the pathological prion protein (PrP<sup>Sc</sup>) in two goats, the investigation of goat prions became of greater interest. Therefore, a broad collection of European...

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Principais autores: Sonja Ernst, Romolo Nonno, Jan Langeveld, Olivier Andreoletti, Cristina Acin, Penelope Papasavva-Stylianou, Theodoros Sklaviadis, Pier Luigi Acutis, Lucien van Keulen, John Spiropoulos, Markus Keller, Martin H. Groschup, Christine Fast
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2024-07-01
Series:Pathogens
Assuntos:
classical scrapie
atypical scrapie
CH1641-like
strain typing
goat
transgenic mice
Acceso en liña:https://www.mdpi.com/2076-0817/13/8/629
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