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Selection and characterization of a DNA aptamer for Patulin and its application in a label-free fluorescence assay for fruit juices

Abstract Patulin (PTL, 154 Da) is a small molecule toxin produced as a mold metabolite. PTL is unstable in animals and is quickly converted to its metabolites. Thus, few successful antibodies were reported even after extensive efforts in hapten design. In this work, a library immobilization strategy...

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Autors principals: Sihan Wang, Jiayi Liang, Haiyang Jiang, Jianzhong Shen, Zhanhui Wang, Juewen Liu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2025-12-01
Col·lecció:One Health Advances
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Accés en línia:https://doi.org/10.1186/s44280-025-00101-2
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