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Monocyte Infiltration and Differentiation in 3D Multicellular Spheroid Cancer Models

Tumor-associated macrophages often correlate with tumor progression, and therapies targeting immune cells in tumors have emerged as promising treatments. To select effective therapies, we established an in vitro 3D multicellular spheroid model including cancer cells, fibroblasts, and monocytes. We a...

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Principais autores: Natasha Helleberg Madsen, Boye Schnack Nielsen, Son Ly Nhat, Søren Skov, Monika Gad, Jesper Larsen
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2021-07-01
סדרה:Pathogens
נושאים:
3D cancer cell models
multicellular spheroids
tumor-associated macrophages
tumor microenvironment
drug screening
in vitro assay
גישה מקוונת:https://www.mdpi.com/2076-0817/10/8/969
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