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Triggering of Suicidal Erythrocyte Death by Topotecan

Background/Aims: The topoisomerase I inhibitor topotecan is used as treatment of various malignancies. The substance is effective by triggering tumor cell apoptosis. In analogy to apoptosis of nucleated cells, erythrocytes may enter eryptosis, a suicidal death characterized by cell shrinkage and cel...

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Hlavní autoři: Rosi Bissinger, Ghada Bouguerra, Katja Stockinger, Salem Abbès, Florian Lang
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Physiol Biochem Press GmbH & Co KG 2015-11-01
Edice:Cellular Physiology and Biochemistry
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On-line přístup:http://www.karger.com/Article/FullText/438527
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