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Targeting late-stage non-small cell lung cancer with a combination of DNT cellular therapy and PD-1 checkpoint blockade

Abstract Background Though immune checkpoint blockade (ICB) against PD-1 has shown success in the treatment of lung cancer, not all patients respond. We have previously shown that adoptive transfer of double negative T (DNT) cells expanded from healthy donors can target leukemia but their role in tr...

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Bibliografiske detaljer
Principais autores: Linan Fang, Dalam Ly, Si-si Wang, Jong Bok Lee, Hyeonjeong Kang, Hao Xu, Junlin Yao, Ming-sound Tsao, Wei Liu, Li Zhang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-03-01
Serier:Journal of Experimental & Clinical Cancer Research
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Online adgang:http://link.springer.com/article/10.1186/s13046-019-1126-y
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