Disruption of the Phosphate Transporter Pit1 in Hepatocytes Improves Glucose Metabolism and Insulin Signaling by Modulating the USP7/IRS1 Interaction

The liver plays a central role in whole-body lipid and glucose homeostasis. Increasing dietary fat intake results in increased hepatic fat deposition, which is associated with a risk for development of insulin resistance and type 2 diabetes. In this study, we demonstrate a role for the phosphate ino...

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Bibliografiske detaljer

Principais autores:	Anne Forand, Eugénie Koumakis, Alice Rousseau, Yohann Sassier, Clément Journe, Jean-François Merlin, Christine Leroy, Valérie Boitez, Patrice Codogno, Gérard Friedlander, Isabelle Cohen
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2016-09-01
Serier:	Cell Reports
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2211124716310580
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