Pazopanib for renal cell carcinoma leads to elevated mean arterial pressures in a murine model

Background: In the setting of metastatic RCC (mRCC), pazopanib is approved as first line therapy. Unfortunately treatment may lead to cardiotoxicity such as hypertension, heart failure, and myocardial ischemia. Objective: Define the in vivo role of pazopanib in the development of cardiotoxicity. Met...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Amber Kempton, Cody Justice, Aaron Guo, Matthew Cefalu, Michael Makara, Paul Janssen, Thai H Ho, Sakima A Smith
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Taylor & Francis Group 2018-08-01
श्रृंखला:	Clinical and Experimental Hypertension
विषय:	renal cell carcinoma hypertension pazopanib tyrosine kinase inhibitors cardio-oncology
ऑनलाइन पहुंच:	http://dx.doi.org/10.1080/10641963.2017.1403623
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