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CD200 Blockade Modulates Tumor Immune Microenvironment but Fails to Show Efficacy in Inhibiting Tumor Growth in a Murine Model of Melanoma

CD200-CD200R pathway regulates immune responses and has been implicated in the pathogenesis of a number of cancer types. CD200 blockade is considered a strategy for immunotherapy of CD200-positive cancers such as melanoma. Thus, it is critical to understand the potential impacts of CD200 blockade in...

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Príomhchruthaitheoirí: Fatemeh Talebian, Jianyu Yu, Kimberly Lynch, Jin-Qing Liu, William E. Carson, Xue-Feng Bai
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2021-10-01
Sraith:Frontiers in Cell and Developmental Biology
Ábhair:
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fcell.2021.739816/full
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