A cluster of broadly neutralizing IgG against BK polyomavirus in a repertoire dominated by IgM

FACS sorting of patient B cells with fluorescent BKPyV VLPs, followed by 10xGenomics scRNAseq, generated a large dataset of BKPyV-specific antibody sequences, among which we were able to identify and characterize broadly neutralizing antibodies. The BK polyomavirus (BKPyV) is an opportunistic pathog...

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Auteurs principaux:	Ngoc-Khanh Nguyen, Marie-Claire Devilder, Laetitia Gautreau-Rolland, Cynthia Fourgeux, Debajyoti Sinha, Jeremie Poschmann, Maryvonne Hourmant, Céline Bressollette-Bodin, Xavier Saulquin, Dorian McIlroy
Format:	Artigo
Langue:	Inglês
Publié:	Life Science Alliance LLC 2023-04-01
Collection:	Life Science Alliance
Accès en ligne:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202201567
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