PFI-3 induces vasorelaxation with potency to reduce extracellular calcium influx in rat mesenteric artery

Background PFI-3 is a small-molecule inhibitor that targets the bromodomains (BRDs) of Brahma-related gene 1 (BRG1). This monomeric compound, which has high selectivity and potent cellular effects, has recently been developed. Although PFI-3 has been reported as a potential therapeutic agent targeti...

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Auteurs principaux:	Jing Li, Xue-Qi Liang, Yun-Feng Cui, Yu-Yang Fu, Zi-Yue Ma, Ying-Tao Cui, Xian-Hui Dong, Hai-Jun Huang, Ting-Ting Tong, Ya-Mei Zhu, Ya-Dong Xue, Yong-Zhen Wang, Tao Ban, Rong Huo
Format:	Artigo
Langue:	Inglês
Publié:	PeerJ Inc. 2023-05-01
Collection:	PeerJ
Sujets:	PFI-3 Vasoconstriction Vasodilation Calcium channels
Accès en ligne:	https://peerj.com/articles/15407.pdf
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