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3β-hydroxysterol δ24-reductase on the surface of hepatitis C virus-related hepatocellular carcinoma cells can be a target for molecular targeting therapy.

In our previous study, we demonstrated that 3β-hydroxysterol Δ24-reductase (DHCR24) was overexpressed in hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), and that its expression was induced by HCV. Using a monoclonal antibody against DHCR24 (2-152a MAb), we found that DHCR24 was speci...

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Hlavní autoři: Makoto Saito, Takashi Takano, Tomohiro Nishimura, Michinori Kohara, Kyoko Tsukiyama-Kohara
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2015-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC4395381?pdf=render
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