The prognostic significance of incomplete hematological recovery in pediatric patients with low/intermediate risk AML and negative MRD after induction 1

BackgroundPediatric acute myeloid leukemia (AML) accounts for approximately 25% of childhood hematologic malignancies. Outcomes have markedly improved, especially in low-risk and intermediate-risk patients, with overall survival (OS) rates approaching 80–85%. Prognosis is primarily determined by cyt...

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Hauptverfasser:	Nessma M. Shahin, Mahmoud Hammad, Hanafy Hafez, Sherine Salem, Nahla El-Sharkawy, Amr Elnashar, Leslie Lehmann, Alaa El-Haddad
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-10-01
Schriftenreihe:	Frontiers in Oncology
Schlagworte:	pediatric acute myeloid leukemia (AML) minimal residual disease (MRD) complete remission (CR) incomplete remission (CRi) morphological remission
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1661036/full
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