Potential role of KRAB-ZFP binding and transcriptional states on DNA methylation of retroelements in human male germ cells
DNA methylation, repressive histone modifications, and PIWI-interacting RNAs are essential for controlling retroelement silencing in mammalian germ lines. Dysregulation of retroelement silencing is associated with male sterility. Although retroelement silencing mechanisms have been extensively studi...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications Ltd
2022-03-01
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| Serier: | eLife |
| Fag: | |
| Online adgang: | https://elifesciences.org/articles/76822 |
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