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Peripheral blood DNA methylation changes are predictive of incident radiographic osteoarthritis development: Data and biospecimens from the osteoarthritis initiative

Objective: The lack of biomarkers to predict knee osteoarthritis (OA) progression is a key unmet need in the OA field. The objective of this study was to evaluate epigenetic changes in baseline peripheral blood cells of healthy individuals who subsequently developed radiographic knee OA (incident OA...

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Principais autores: Cindy Miranda Brawner, Gabriella Dyson, Montana Barrett, Nicholas Hanebutt, Aleksander Szymczak, Padmaja Mehta-D’souza, Matlock A. Jeffries
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-12-01
coleção:Osteoarthritis and Cartilage Open
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2665913125001281
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