Macrophages in osteoporotic fractures: from immunometabolic mechanisms to precision therapeutic approaches

Osteoporosis (OP) is a systemic bone disease characterized by reduced bone mass and deterioration of bone microarchitecture. Its critical complication, osteoporotic fractures (OPF), imposes a significant global disease burden. Macrophages, serving as central regulators within the osteoimmune microen...

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Bibliografische Detailangaben

Hauptverfasser:	Jiahui Xing, Haibo Li, Honggang Xia, Lilei Xia, Hongzhou Zhao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-11-01
Schriftenreihe:	Frontiers in Endocrinology
Schlagworte:	osteoporotic fractures macrophages immunometabolism metabolic reprogramming polarization targeted therapy
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1698647/full
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