Piceid Octanoate Protects Retinal Cells against Oxidative Damage by Regulating the Sirtuin 1/Poly-ADP-Ribose Polymerase 1 Axis In Vitro and in rd10 Mice

Retinitis pigmentosa is a common cause of inherited blindness in adults, which in many cases is associated with an increase in the formation of reactive oxygen species (ROS) that induces DNA damage, triggering Poly-ADP-Ribose Polymerase 1 (PARP1) activation and leading to parthanatos-mediated cell d...

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Principais autores:	Seyed Mohamadmehdi Moshtaghion, Estefanía Caballano-Infantes, Álvaro Plaza Reyes, Lourdes Valdés-Sánchez, Patricia Gallego Fernández, Berta de la Cerda, Maurizio S. Riga, Manuel Álvarez-Dolado, Pablo Peñalver, Juan C. Morales, Francisco J. Díaz-Corrales
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2024-02-01
Series:	Antioxidants
Assuntos:	retinal degeneration retinitis pigmentosa oxidative stress mitochondrial dysfunction reactive oxygen species (ROS) parthanatos
Acceso en liña:	https://www.mdpi.com/2076-3921/13/2/201
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