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Common crosstalk genes and molecular mechanisms in Helicobacter pylori infection and colorectal cancer

Abstract Epidemiological evidence indicates that HP-I increases the risk of CRC, yet the underlying pathological mechanisms remain unclear. This study aimed to identify DEGs associated with HP-I and CRC by analyzing public RNA sequencing data and to investigate potential molecular pathways. Gene exp...

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Main Authors: Na Wei, Yao-Hui Ma, Ling-Zhu Gou, Tong Lu, Xinglan Chen, Dekui Zhang
Format: Artigo
Language:Inglês
Published: Springer 2026-04-01
Series:Discover Oncology
Subjects:
Helicobacter pylori
Colorectal cancer
Immune infiltration
Molecular mechanism
Molecular docking
Online Access:https://doi.org/10.1007/s12672-026-04866-9
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