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The RAD51 recombinase protects mitotic chromatin in human cells

RAD51 is a well known player of DNA repair and homologous recombination. Here the authors reveal a function for RAD51 in protecting under-replicated DNA in mitotic human cells, promoting mitotic DNA synthesis (MiDAS) and successful chromosome segregation.

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Bibliografische Detailangaben
Hauptverfasser: Isabel E. Wassing, Emily Graham, Xanita Saayman, Lucia Rampazzo, Christine Ralf, Andrew Bassett, Fumiko Esashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2021-09-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/s41467-021-25643-y
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