Quantifying Radiosensitization of PSMA-Targeted Gold Nanoparticles on Prostate Cancer Cells at Megavoltage Radiation Energies by Monte Carlo Simulation and Local Effect Model

Active targeting gold nanoparticles (AuNPs) are a very promising avenue for cancer treatment with many publications on AuNP mediated radiosensitization at kilovoltage (kV) photon energies. However, uncertainty on the effectiveness of AuNPs under clinically relevant megavoltage (MV) radiation energie...

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Autori principali:	Ryder M. Schmidt, Daiki Hara, Jorge D. Vega, Marwan B. Abuhaija, Wensi Tao, Nesrin Dogan, Alan Pollack, John C. Ford, Junwei Shi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-10-01
Serie:	Pharmaceutics
Soggetti:	gold nanoparticle nanoparticle enhanced radiation therapy Monte Carlo local effect model dose enhancement ratio sensitization enhancement ratio
Accesso online:	https://www.mdpi.com/1999-4923/14/10/2205
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