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Synthesis and biological evaluation of anthracene-9,10 dione derivatives as CK2 inhibitors

Human protein kinase CK2 is an important target for the development of anticancer drugs. Many inhibitors were developed in the last few decades, among them emodin, a natural inhibitor with anthracene-9,10-dione backbone. In this work the inhibitory activity of another natural compound endocrocin hav...

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主要な著者: Priscila López-Rojas, Samer Haidar, Franziska M. Jürgens, Dagmar Aichele, Ángel Amesty, Ana Estévez-Braun, Joachim Jose
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2023-12-01
シリーズ:Results in Chemistry
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オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2211715623002369
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