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Syncytiotrophoblast Extracellular Vesicles From Late-Onset Preeclampsia Placentae Suppress Pro-Inflammatory Immune Response in THP-1 Macrophages

Syncytiotrophoblast derived Extracellular Vesicles (STBEV) from normal pregnancy (NP) have previously been shown to interact with circulating monocytes and B cells and induce pro-inflammatory cytokine release. Early-onset preeclampsia (EOPE) is associated with an exacerbated inflammatory response, y...

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Principais autores: Toluwalase Awoyemi, Carolina Motta-Mejia, Wei Zhang, Lubna Kouser, Kirsten White, Neva Kandzija, Fatimah S. Alhamlan, Adam P. Cribbs, Dionne Tannetta, Emily Mazey, Christopher Redman, Uday Kishore, Manu Vatish
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-06-01
coleção:Frontiers in Immunology
Assuntos:
preeclampsia
vesicles
inflammation
placenta
THP-1 cells
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2021.676056/full
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