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Vemurafenib inhibits immune escape biomarker BCL2A1 by targeting PI3K/AKT signaling pathway to suppress breast cancer

ObjectivesTo investigate the role of immune escape encoding genes on the prognosis of BC, and to predict the novel targeting agents.MethodsHuman immune genes and immune escape encoding genes were obtained from the IMMPORT database and the previous study. Sample information and clinical data on BC we...

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Sábháilte in:
Príomhchruthaitheoirí: Yalan Dai, Liqiong Yang, Abass Sakandar, Duoli Zhang, Fukuan Du, Xinyi Zhang, Linglin Zou, Yueshui Zhao, Jigang Wang, Zhenhua Zhang, Xu Wu, Mingxing Li, Xiao Ling, Lei Yu, Lishu Dong, Jing Shen, Zhangang Xiao, Qinglian Wen
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2022-11-01
Sraith:Frontiers in Oncology
Ábhair:
Immune escape
breast cancer
prognostic model
bioinformatics
biomarker
BCL2A1
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fonc.2022.906197/full
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