Computational insights into the inhibitory potential of dihydroorotate dehydrogenase by natural compounds in Artocarpus Champeden as antimalarial agents

Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) is a crucial target for the development of antimalarial drugs, as it plays a significant role in inhibiting the growth of parasites by disrupting the production of pyrimidines in the bloodstream. Artocarpus champeden is known to contain pr...

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Detalhes bibliográficos

Principais autores:	Tjitda Putra Jiwamurwa Pama, Nitbani Febri Odel, Wahyuningsih Tutik Dwi, Abanit Yohanes Mau, Soeharto Faizal Riza
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Serbian Chemical Society 2025-01-01
coleção:	Journal of the Serbian Chemical Society
Assuntos:	molecular docking molecular dynamics plasmodium falciparum malaria natural product
Acesso em linha:	https://doiserbia.nb.rs/img/doi/0352-5139/2025/0352-51392500057T.pdf
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