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Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function

N-docosahexaenoylethanolamine (synaptamide) promotes neurogenesis but the molecular mechanism involved is unknown. Here, the authors show that orphan G-protein coupled receptor 110 is the synaptamide receptor, with deletion in mice affecting development of neurons, object recognition and spatial mem...

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Detalhes bibliográficos
Principais autores: Ji-Won Lee, Bill X. Huang, HeungSun Kwon, Md Abdur Rashid, Giorgi Kharebava, Abhishek Desai, Samarjit Patnaik, Juan Marugan, Hee-Yong Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2016-10-01
coleção:Nature Communications
Acesso em linha:https://doi.org/10.1038/ncomms13123
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