Efficacy and Safety of Chimeric Antigen Receptor T Cells in Acute Lymphoblastic Leukemia With Post-Transplant Relapse

Twenty patients with relapsed B-ALL after HSCT were treated with CAR T cell therapy and were evaluated for efficacy and safety. Twelve patients previously received haploidentical transplantation, while 8 patients received HLA-matched transplantation. The median relapse time was 12 months (range, 4 t...

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Detalhes bibliográficos

Principais autores:	Lijuan Ding, Yiyun Wang, Ruimin Hong, Houli Zhao, Linghui Zhou, Guoqing Wei, Wenjun Wu, Huijun Xu, Yanlei Zhang, Yi Luo, Jimin Shi, Alex H. Chang, Yongxian Hu, He Huang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-11-01
coleção:	Frontiers in Oncology
Assuntos:	chimeric antigen receptor T cells post-transplant relapse acute graft versus host disease cytokine release syndrome acute lymphoblastic leukemia
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fonc.2021.750218/full
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