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Evaluation of Critical Quality Attributes of a Pentavalent (A, C, Y, W, X) Meningococcal Conjugate Vaccine for Global Use

Towards achieving the goal of eliminating epidemic outbreaks of meningococcal disease in the African meningitis belt, a pentavalent glycoconjugate vaccine (NmCV-5) has been developed to protect against <i>Neisseria meningitidis</i> serogroups A, C, Y, W and X. MenA and X polysaccharides are conjugat...

Ausführliche Beschreibung

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Hauptverfasser: Barbara Bolgiano, Eilís Moran, Nicola J. Beresford, Fang Gao, Rory Care, Trusha Desai, Ida Karin Nordgren, Timothy R. Rudd, Ian M. Feavers, Prashant Bore, Sushil Patni, Vinay Gavade, Asha Mallya, Sameer Kale, Pankaj Sharma, Sunil K. Goel, Sunil Gairola, Suhas Hattarki, Nikhil Avalaskar, Annamraju D. Sarma, Marc LaForce, Neil Ravenscroft, Lakshmi Khandke, Mark R. Alderson, Rajeev M. Dhere, Sambhaji S. Pisal
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-07-01
Schriftenreihe:Pathogens
Schlagworte:
<i>Neisseria meningitidis</i>
glycoconjugates
meningitis
adjuvant
chromatography
immunogenicity
Online-Zugang:https://www.mdpi.com/2076-0817/10/8/928
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