Advances in targeting cancer-associated fibroblasts through single-cell spatial transcriptomic sequencing

Abstract Cancer-associated fibroblasts (CAFs) are the major components of the tumor microenvironment and are related to tumor proliferation, metastasis, relapse, and drug resistance. With the development of sequencing technologies, single-cell RNA sequencing has become a popular method for identifyi...

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Principais autores:	Pin Lyu, Xiaoming Gu, Fuqi Wang, Haifeng Sun, Quanbo Zhou, Shuaixi Yang, Weitang Yuan
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2024-07-01
Series:	Biomarker Research
Assuntos:	Single-cell spatial transcriptomic sequencing Cancer associated fibroblast Drug resistance Angiogenesis and metastasis Metabolic reprogramming
Acceso en liña:	https://doi.org/10.1186/s40364-024-00622-9
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