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Utilizing Regulatory T Cells Against Rheumatoid Arthritis

Regulatory T (Treg) cells are essential for normal immune surveillance systems, and their dysfunction leads to development of diseases, such as autoimmune disorders. CD4+ CD25+ Treg cells are well-known suppressive cells which express the transcription factor Foxp3, are indispensable for the mainten...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Mohammad eHaque, Kristin eFino, Fengyang eLei, Xiaofang eXiong, Jianxun eSong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014-08-01
Schriftenreihe:Frontiers in Oncology
Schlagworte:
Autoimmunity
Stem Cells
regulatory T cells
rheumatoid arthritis (RA)
cell-based therapies
suppressive cytokines
Online-Zugang:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00209/full
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