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Building a predictive model for polycyclic aromatic hydrocarbon dosimetry in organotypically cultured human bronchial epithelial cells using benzo[a]pyrene

The airway epithelium is a primary route of exposure for inhaled toxicants, and organotypic culture models represent an important advancement for toxicity testing compared to simple in vitro models that may lack metabolic capability and multicellular structure/communication associated with the bronc...

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Hauptverfasser: Victoria C. Colvin, Kelley M. Bastin, Lisbeth K. Siddens, Monica L. Vermillion Maier, David E. Williams, Jordan N. Smith, Susan C. Tilton
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2025-12-01
Schriftenreihe:Toxicology Reports
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2214750025002525
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