Attenuation of a Pathogenic <italic toggle="yes">Mycoplasma</italic> Strain by Modification of the <italic toggle="yes">obg</italic> Gene by Using Synthetic Biology Approaches

ABSTRACT Mycoplasma species are responsible for several economically significant livestock diseases for which there is a need for new and improved vaccines. Most of the existing mycoplasma vaccines are attenuated strains that have been empirically obtained by serial passages or by chemical mutagenes...

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主要な著者:	Carole Lartigue, Yanina Valverde Timana, Fabien Labroussaa, Elise Schieck, Anne Liljander, Flavio Sacchini, Horst Posthaus, Brigitte Batailler, Pascal Sirand-Pugnet, Sanjay Vashee, Joerg Jores, Alain Blanchard
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology 2019-06-01
シリーズ:	mSphere
主題:	GTPase Obg Mycoplasma Saccharomyces cerevisiae attenuated strain genome engineering genome transplantation
オンライン･アクセス:	https://journals.asm.org/doi/10.1128/mSphere.00030-19
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