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Co-exposure of microcystin and nitrite enhanced spermatogenic disorders: The role of mtROS-mediated pyroptosis and apoptosis

Microcystins (MCs) and nitrites are coexisted in the environment and have reproductive toxicity. The combined toxic effect and mechanism of MCs and nitrite on spermatogenesis remain largely unclear. In the present study, co-exposure to microcystin-leucine arginine (MC-LR) and sodium nitrite (NaNO2)...

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Principais autores: Haohao Liu, Xingde Du, Zongxin Zhang, Kangfeng Ge, Xinghai Chen, Michael D. Losiewicz, Hongxiang Guo, Huizhen Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-06-01
coleção:Environment International
Assuntos:
Microcystins
Nitrite
Spermatogenic disorders
Mitochondrial oxidative impairment
Reproductive toxicity
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S016041202400357X
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