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Hexasodium fytate for the treatment of calciphylaxis: a randomised, double-blind, phase 3, placebo-controlled trial with an open-label extensionResearch in context

Summary: Background: In the CALCIPHYX trial, we investigated hexasodium fytate, an inhibitor of vascular calcification, for the treatment of calcific uraemic arteriolopathy (calciphylaxis), a rare condition characterised by painful, non-healing skin lesions. Methods: In this international, phase 3,...

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Principais autores: Smeeta Sinha, Sagar U. Nigwekar, Vincent Brandenburg, Lisa J. Gould, Thomas E. Serena, Sharon M. Moe, George R. Aronoff, Dinesh K. Chatoth, Jeffrey L. Hymes, Kevin J. Carroll, Gabriela Alperovich, Laurence H. Keller, Joan Perelló, Alex Gold, Glenn M. Chertow
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-09-01
Serier:EClinicalMedicine
Fag:
Calciphylaxis
Calcific uraemic arteriolopathy
Dialysis
SNF472
Hexasodium fytate
Calcification
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589537024003638
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