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Two-way Dispatched function in Sonic hedgehog shedding and transfer to high-density lipoproteins

The Sonic hedgehog (Shh) signaling pathway controls embryonic development and tissue homeostasis after birth. This requires regulated solubilization of dual-lipidated, firmly plasma membrane-associated Shh precursors from producing cells. Although it is firmly established that the resistance-nodulat...

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Bibliografiske detaljer
Principais autores: Kristina Ehring, Sophia Friederike Ehlers, Jurij Froese, Fabian Gude, Janna Puschmann, Kay Grobe
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2024-09-01
Serier:eLife
Fag:
Online adgang:https://elifesciences.org/articles/86920
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