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Inhibition of Metalloproteinases Extends Longevity and Function of In Vitro Human iPSC-Derived Skeletal Muscle

In vitro culture longevity has long been a concern for disease modeling and drug testing when using contractable cells. The dynamic nature of certain cells, such as skeletal muscle, contributes to cell surface release, which limits the system’s ability to conduct long-term studies. This study hypoth...

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Principais autores: Natali Barakat, Himanshi Jangir, Leandro Gallo, Marcella Grillo, Xiufang Guo, James Hickman
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2024-04-01
סדרה:Biomedicines
נושאים:
metalloproteinases
extracellular matrix
human iPSC-derived skeletal muscle
cell adhesion
גישה מקוונת:https://www.mdpi.com/2227-9059/12/4/856
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