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Culture of pluripotent stem cells in microscale droplets modulates differentiation and tissue patterning towards organoids on chip

Abstract Background The differentiation of pluripotent stem cells (PSCs) and their self-organization into organoids are influenced by cell-cell interactions mediated by contacts and secreted molecules. These interactions are enhanced in microfluidic droplets due to confinement and small culture volu...

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Auteurs principaux: Nadia Vertti-Quintero, Clara Delahousse, Andrey Aristov, Tatiana Traboulsi, Jack-Christophe Cossec, Charles N. Baroud, Sébastien Sart
Format: Artigo
Langue:Inglês
Publié: BMC 2025-09-01
Collection:Stem Cell Research & Therapy
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Accès en ligne:https://doi.org/10.1186/s13287-025-04625-7
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