Unique characteristics of the tumor immune microenvironment in young patients with metastatic colorectal cancer

IntroductionMetastatic colorectal cancer (mCRC) remains a common and highly morbid disease, with a recent increase in incidence in patients younger than 50 years. There is an acute need to better understand differences in tumor biology, molecular characteristics, and other age-related differences in...

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Hlavní autoři:	Brian D. Griffith, Jenny Lazarus, Jake McGue, Santhoshi Krishnan, Michael I. D’Angelica, Jinru Shia, Irina Dobrosotskaya, Jaiqi Shi, Jacob Edwards, Arvind Rao, Timothy L. Frankel
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-12-01
Edice:	Frontiers in Immunology
Témata:	tumor immunology colorectal cancer immunotherapy spatial relation analysis multiplex immunohistochemistry (IHC)
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1289402/full
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