Transient restructuring of the active oral resistome during probiotic Streptococcus salivarius K12 colonization in a 3D polymicrobial biofilm model

Background The oral cavity harbours a complex and transcriptionally active antibiotic resistance gene (ARG) reservoir shaped by polymicrobial biofilm ecology. Whether probiotic-mediated ecological modulation can remodel the active resistome without promoting horizontal gene transfer remains poorly u...

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Autori principali:	Nadeeka S. Udawatte, Chun Liu, Reuben Staples, Pingping Han, Purnima S. Kumar, Thiruma V. Arumugam, Sašo Ivanovski, Chaminda Jayampath Seneviratne
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis Group 2026-12-01
Serie:	Journal of Oral Microbiology
Soggetti:	Streptococcus salivarius K12 oral bacteria probiotic colonization active resistome modulation metatranscriptomics antibiotic resistance genes (ARGs)
Accesso online:	https://www.tandfonline.com/doi/10.1080/20002297.2026.2680793
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