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MicroRNAs as regulators of immune checkpoints in cancer immunotherapy: targeting PD-1/PD-L1 and CTLA-4 pathways

Abstract Immunotherapy has revolutionized cancer treatment by harnessing the power of the immune system to eliminate tumors. Immune checkpoint inhibitors (ICIs) block negative regulatory signals that prevent T cells from attacking cancer cells. Two key ICIs target the PD-1/PD-L1 pathway, which inclu...

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Hlavní autoři: Arefeh Zabeti Touchaei, Sogand Vahidi
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2024-03-01
Edice:Cancer Cell International
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On-line přístup:https://doi.org/10.1186/s12935-024-03293-6
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