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The BRCA1/BARD1 complex recognizes pre-ribosomal RNA to facilitate homologous recombination

Abstract The BRCA1/BARD1 complex plays a key role in the repair of DNA double-strand breaks (DSBs) in both somatic cells and germ cells. However, the underlying molecular mechanism by which this complex mediates DSB repair is not fully understood. Here, we examined the XY body of male germ cells, wh...

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Detalhes bibliográficos
Principais autores: Duo Wu, Huang Huang, Tenglong Chen, Xiaochen Gai, Qilin Li, Chunhui Wang, Jia Yao, Yu Liu, Shang Cai, Xiaochun Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2023-10-01
Colecção:Cell Discovery
Acesso em linha:https://doi.org/10.1038/s41421-023-00590-8
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