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Delayed-Release Dimethyl Fumarate Safety and Efficacy in Pediatric Patients With Relapsing-Remitting Multiple Sclerosis

Background: Pediatric multiple sclerosis (MS) is rare: only 1.5–5% of MS cases are diagnosed before 18 years of age, and data on disease-modifying therapies (DMTs) for pediatric MS are limited. The CONNECTED study assessed the long-term safety and efficacy of treatment with delayed-release dimethyl...

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Principais autores: Raed Alroughani, Peter Huppke, Maria Mazurkiewicz-Beldzinska, Astrid Blaschek, Martin Valis, Gregory Aaen, Joe Pultz, Xiaomei Peng, Vanessa Beynon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-01-01
coleção:Frontiers in Neurology
Assuntos:
relapsing-remitting multiple sclerosis
dimethyl fumarate
safety
efficacy
pediatric
pharmacokinetics
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fneur.2020.606418/full
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