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Dual response of BDNF to sublethal concentrations of β-amyloid peptides in cultured cortical neurons

Beta-amyloid (Aβ) deposition is one important pathological hallmark in Alzheimer's disease (AD). However, low levels of Aβ may modify critical endogenous protection systems before neurodegeneration occurs. We examined the time-course effect of sublethal concentrations of Aβ on total BDNF (panBDNF),...

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Bibliographic Details
Main Authors: E. Aliaga, M. Silhol, N. Bonneau, T. Maurice, S. Arancibia, L. Tapia-Arancibia
Format: Artigo
Language:Inglês
Published: Elsevier 2010-01-01
Series:Neurobiology of Disease
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Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109002812
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