IFITM3 variants point to a critical role in emergent virus infections

ABSTRACT Interferon-induced transmembrane protein 3 (IFITM3) is a cellular protein that restricts numerous viral infections by blocking virus–host membrane fusion. In humans, there are two IFITM3 single nucleotide polymorphisms (SNPs), rs12252-C and rs34481144-A, that decrease IFITM3 activity and ha...

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Үндсэн зохиолчид:	Parker J. Denz, Jacob S. Yount
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology 2025-05-01
Цуврал:	mBio
Нөхцлүүд:	IFITM3 influenza virus SARS-CoV-2 innate immunity SNP emerging viruses
Онлайн хандалт:	https://journals.asm.org/doi/10.1128/mbio.03347-24
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!